An instrument which uses both direction and velocity focusing, and therefore an ion beam initially diverging in direction and containing ions of different kinetic energies is separated into beams according to the quotient mass charge, these beams being focused on to a. Us4924090a double focusing mass spectrometer and msms. Double focus mass spectrometer time of flight analyzers nonmagnetic separation detector electron multiplier tube instantaneous display of results fig. Small general purpose double focusing mass spectrometer. The jeol double focusing jms mstation spectrometer has an upper mass of. A new ion optical system of the miniature doublefocusing mass spectrograph was designed by trio 2. The fragmentations on electronimpact of two piperazinodibenza zepine drugs with cns activity are investigated by high and low resolution mass spectrometry, direct analysis of daughter ions dadi and defocussing metastable techniques, as well as deuterium labelling. These sessions included an externalarray quadrupole ion trap r. Designed to work with virtually any source of externally generated ions. Development of miniature doublefocusing mass spectrograph. Field ionisation studies using a double focus sing mass spectrometer. Development of an insitu mass spectrometer for stable. A doublefocusing magnetic mass spectrometer for satellite use.
A popular combination of these sectors has been the beb magneticelectricmagnetic. Designed specifically to do tofms with ions created from an external source. Doublefocusing mass spectrometer mass spectrometry terms. A doublefocusing mass spectrometer combining the homogeneous fields of a wien filter and a magnet was built by jordan 461. Double focusing mass analyzer, instrumentation of mass spectrometry, mass spectrometry, magnetic field deflection mass analyser, time of. An introduction to ion optics for the mass spectrograph uni ulm.
Ionization chamber is used to ionize the gas whose mass or isotope is to be determined and positive ions are produced. Title atomic masses and neutron separation energies for some isotopes of cadmium. Ambrose college, davenport, iowa, 1955 a thesis submitted in partial fulfillment of the requirements for the degree master op science department of physics kansas state college op agriculture and applied science 1958 lp. The divergent monoenergetic beam contains two ion species of different mass tocharge ratio. An essential feature of the geometry is that it eliminates secondorder angular aberration, enhancing the. Development of mass spectrometers from thomson and aston to. Secondorder doublefocusing mass spectrograph with a wide. Nier at the university of minnesota developed the high mass resolution double focusing instrument during world war ii to perform isotopic analysis and separate 235u from 238u 3. Introduction uses of mass spec louisiana tech university. Single quadrupole gcms thermo fisher scientific us. Dempster devoted much of his career almost exclusively to a single taskthat of using mass spectrometry techniques to discover stable isotopes of the chemical elements and their relative abundances.
Mass spectrometry and allied topics, may 2227, 1966, dallas, tex. As a laboratory instrument for making gas or isotope analyses, its sensitivity and resolution make it competitive with instruments several times as large employing only a. After a short summary of the theory of double focusing a mass spectrograph which works as an achromatic lens for all masses is described in some detail. The ions are deflected in opposite directions in the electrostatic and magnetic fields. The development of a high resolution mass spectrometer. A sector instrument is a general term for a class of mass spectrometer that uses a static electric.
A sector instrument is a general term for a class of mass spectrometer that uses a static electric or magnetic sector or some combination of the two separately in space as a mass analyzer. Since the ion paths through the magnetic sector are reversible, two ions of the same mass but different kinetic energies will be recombined at the detector slit. Double focusing magnetic sector mass analyzers are the classical model against which other mass analyzers are compared. Hall consolidated systems corporation introduction study of the earths upper atmosphere by direct measurement techniques has been a realizable and productive possibility since shortly after world war 11. Lowresolution and gc mass spectra were obtained on a shimadzulkb 9000 gcms spectrometer and highresolution mass spectra were determined on a joel jmso1sg2 double focus mass spectrometer.
Advances in imaging and electron physics, volume 176 1st. Doublefocusing mass spectrometer including a wien filter with. The ion optical system was designed to satisfy the double focusing along a straight line being at a distance from the exit fringe of the magnetic sector to employ a focal plane detector. A doublefocusing mass spectrograph and the masses of n 15 and. He was known for the development of the mattauchherzog double focusing mass spectrometer, for his work on the investigation of isotopic abundances using mass spectrometry, and. Time of flight mass spectrometer components from jordan tof products formerly r. This is quite useful in determining a molecular formula for the compound you are attempting to identify. Arrangement of the electrostatic and magnetic sectors in the mattauchherzog doublefocusing mass spectrometer. Mass spectrometry ms gives information about the molecular weight of your compound and, when performed in conjunction with a combustion analysis, the relative percentages of carbon, hydrogen, and oxygen present. Quadrupole analyzers 4 short parallel metal rods opposite rods same charge on dc.
The large double focusing mass spectrometer operating at its theoretical resolving power of more than 100,000 at the base of the peaks has been used to measure. Sector mass spectrometer wikimili, the best wikipedia reader. A doublefocusing mass spectrograph is an instrument which uses both direction. A sector instrument is a general term for a class of mass spectrometer that utilizes a static electric or magnetic sector or some combination of the two separately in space as a mass analyzer. Why do double focusing mass spectrometers give narrower peaks and higher resolutions than single focusing instruments. General disclaimer one or more of the following statements. Preliminary report on a large mass spectrograph newly. The first is the double focusing mass spectrometer constructed by bondy, johannsen, and poppers6 according modern mass spectroscopy 247 to the theory developed earlier by bartky and dempster. Most modern sector instruments are double focusing instruments in that they focus the ion beams both in direction and.
Advances in imaging and electron physics features cuttingedge articles on the physics of electron devices especially semiconductor devices, particle optics at high and low energies, microlithography, image science and digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these. The advantages of simultaneous detection are straight forward. Bainbridge and jordan double focussing mass spectrograph. International journal of mass spectrometry and ion processes, 91 1989 1926 19 elsevier science publishers b. One or more of the following statements may affect this document. S b a mass spec timeline hailey g russell s and ary. Design and performance of a high resolution electrospray. Their mass spectrometer, based on the mattauchherzog design3,4, is ideal for simultaneous detection, as it provides a linear double focus angle and energy over a very large mass range. Velocity selector has two fields electric and magnetic field both are applied perpendicular to the moving ion beam. The radius of curvature of ion paths in the magnetic analyzer is 2 in. The secondorder coefficients of the double focusing mass spectrograph which consists of a cylindri. Most modern sector instruments are doublefocusing instruments first developed by a. A new large mass spectrograph of double focusing type was constructed at osaka university. When mass spectrographs with high resolving power or high optical brightness are designed, the secondorder terms can not be neglected, though its calculation is a very tedious work.
In order to provide a compact and constructionally simple arrangement, it is proposed that a common magnet is used for the wien filter 10 and the sector magnet 11. Existing jordan tof instruments can be easily retrofitted to orthogotof. Atomic masses and neutron separation energies for some. Comparison of the jmss3000 spiraltoftof and a 4sector.
Ord and cd spectra were recorded on a jasco j20 spectropolarimeter. T3 sector type and 2 ji3 cylindrical electric field. Most modern sector instruments are double focusing instruments first developed by. Graham cooks, the labonachip using the miniaturized quadrupole ion trap michael ramsey, two different concepts of a double focusing magneticsector mass spectrometer jorge a. An instrument which uses both direction and velocity focusing. The magnetic sector radius is nominally 780 mm and the electric sector radius is mm. Best quantitative performance of all mass spectrometer analyzers. Most modern sector instruments are double focusing instruments first developed by a. When one detects more than one mass at a time, less signal is wasted. Mass spectrometry double focusing mass spectrometer. Bainbridge mass spectrograph engineering physics class. Second order doublefocusing mass spectrograph with a wide.
Test of a miniature doublefocusing mass spectrometer for. Preferably, this double focusing mass spectrometer is used in an msms. Matrix representation for calculation of the secondorder. Full text of evaluation of a mass spectrograph see other formats an evaluation op a mass spectrograph by morris albert calsyn b. In fact, the first nuclear bomb was developed entirely from the uranium separated by this type of mass spectrometer. Chlorine and bromine isotope fractionation of halogenated. Double focusing in general is achieved when ions emerging from an ion. Josef mattauch 21 november 1895 10 august 1976 was a nuclear physicist and chemist. A doublefocusing magnetic mass spectrometer for satellite use by carl a. The invention relates to a double focusing mass spectrometer with a combination of an electric and of a magnetic field for directional and velocity focusing. Ions source slit quadrupole rods resonant ion detected. Fragmentation of piperazinodibenzazepines on electron. Other articles where doublefocusing mass spectrometer is discussed. With nevervent technology for the extractabrite source, its possible to isolate the mass spectrometer from the gas chromatograph, allowing source cleaning, column replacement or injector maintenance, without downtime for venting.
Miniature doublefocusing mass spectrometer design the design of the miniature mass analyzer is based on the mass separation and focusing capabilities of a 90 cylindrical double focusing mass analyzer using crossed electric and magnetic. The design and construction of the double focus sing mass spectrometer employed have been outlined elsewhere 14, 15 and will be discussed in detail in relation to performance in a future paper 16. Klemm 1584 thermodiffusion in nalkan bicycloalkangemischen h 1. Most modern sector instruments are double focusing instruments in that they focus the ion beams both in direction. Conclusions these results clearly demonstrate that the spiraltoftof produced the same structural information as a traditional four sector tandem double focusing mass spectrometer.
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